Trypanosoma cruzi genotypes associated with domestic Triatoma sordida in Bolivia

Simone Frédérique Brenière, Wilson Morochi, Marie France Bosseno, Jackeline Ordoñez, Teresa Gutierrez, Fernando Vargas, Nina Yaksic, François Noireau

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

18 Citas (Scopus)

Resumen

Triatoma sordida is the second species of Triatominae considered of epidemiological significance in Bolivia. Associated with Triatoma infestans in various regions, it is as yet the only triatomine species established in human dwellings in localities of Velasco province, Department of Santa Cruz. This domestication is considered as primary. Flagellate parasites were detected in 16.2% of domiciliary T. sordida and the kDNA-PCR confirmed the presence of Trypanosoma cruzi. Frequencies of T. cruzi clonets 20 and 39, common clonets in Bolivian domestic cycle (T. infestans), were established by their direct detection in feces using PCR and hybridization. These clonets present low frequencies in T. sordida and synanthropic mammals. Forty-six stocks were isolated and analysed by multilocus enzyme electrophoresis (MLEE). The MLEE showed a higher clonal diversity than in T. infestans domestic cycle and the genotypes were clustered in the two principal lineages of T. cruzi. Within each lineage, a broad variability was observed. Mixture of genotypes was mostly observed in mammals. The large diversity of T. cruzi in this cycle should be related to its sylvatic origin. Moreover, the current limited sample of stocks suggests a lineage association with specific hosts. Copyright (C) 1998 Elsevier Science B.V.

Idioma originalInglés
Páginas (desde-hasta)269-283
Número de páginas15
PublicaciónActa Tropica
Volumen71
N.º3
DOI
EstadoPublicada - 30 nov. 1998
Publicado de forma externa

Nota bibliográfica

Funding Information:
This study received financial support from the United Nations Development Program/World Bank/WHO Special Program for Research and Training in Tropical Disease (grant 940209).

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