Serodiagnosis of Chronic and Acute Chagas' Disease with Trypanosoma cruzi Recombinant Proteins: Results of a Collaborative Study in Six Latin American Countries

Eufrosina S. Umezawa, Alejandro O. Luquetti, Gabriela Levitus, Carlos Ponce, Elisa Ponce, Diana Henriquez, Susana Revollo, Bertha Espinoza, Octavio Sousa, Baldip Khan, José Franco Da Silveira

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

59 Citas (Scopus)

Resumen

An enzyme-linked immunosorbent assay to diagnose Chagas' disease by a serological test was performed with Trypanosoma cruzi recombinant antigens (JL8, MAP, and TcPo). High sensitivity (99.4%) and specificity (99.3%) were obtained when JL8 was combined with MAP (JM) and tested with 150 serum samples from chagasic and 142 nonchagasic individuals. Moreover, JM also diagnosed 84.2% of patients in the acute phase of T. cruzi infection.

Idioma originalInglés
Páginas (desde-hasta)449-452
Número de páginas4
PublicaciónJournal of Clinical Microbiology
Volumen42
N.º1
DOI
EstadoPublicada - ene. 2004
Publicado de forma externa

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Profundice en los temas de investigación de 'Serodiagnosis of Chronic and Acute Chagas' Disease with Trypanosoma cruzi Recombinant Proteins: Results of a Collaborative Study in Six Latin American Countries'. En conjunto forman una huella única.

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