Natural Pseudoguaianolides Prepared from Damsin

R. Villagomez; M. Quiroz; A. Tito; O. Sterner; G. R. Almanza

doi:10.1007/s10600-015-1382-9

Natural Pseudoguaianolides Prepared from Damsin

R. Villagomez, M. Quiroz, A. Tito, O. Sterner, G. R. Almanza

Resultado de la investigación: Contribución a una revista › Artículo › revisión exhaustiva

4 Citas (Scopus)

Resumen

Damsin (1) is a pseudoguaianolide sesquiterpene possessing potent biological activities, reported as a metabolite of several medicinal plants belonging to the genus Ambrosia together with related compounds. Starting from 1, which can be isolated in good amounts from Ambrosia arborescens, the five natural pseudoguaianolides ambrosin (2), isodamsin (3), 3α-hydroxydamsin (4), 3α-acetoxydamsin (5), and 11β,13-dihydrodamsin (8) were prepared by regio- and stereo-selective synthetic modifications.

Idioma original	Inglés
Páginas (desde-hasta)	675-680
Número de páginas	6
Publicación	Chemistry of Natural Compounds
Volumen	51
N.º	4
DOI	https://doi.org/10.1007/s10600-015-1382-9
Estado	Publicada - 22 jul. 2015
Publicado de forma externa	Sí

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© 2015 Springer Science+Business Media New York.

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title = "Natural Pseudoguaianolides Prepared from Damsin",

abstract = "Damsin (1) is a pseudoguaianolide sesquiterpene possessing potent biological activities, reported as a metabolite of several medicinal plants belonging to the genus Ambrosia together with related compounds. Starting from 1, which can be isolated in good amounts from Ambrosia arborescens, the five natural pseudoguaianolides ambrosin (2), isodamsin (3), 3α-hydroxydamsin (4), 3α-acetoxydamsin (5), and 11β,13-dihydrodamsin (8) were prepared by regio- and stereo-selective synthetic modifications.",

keywords = "ambrosanolides, damsin, derivatization, pseudoguaianolides, semi-synthesis, sesquiterpene lactones",

author = "R. Villagomez and M. Quiroz and A. Tito and O. Sterner and Almanza, {G. R.}",

note = "Publisher Copyright: {\textcopyright} 2015 Springer Science+Business Media New York.",

year = "2015",

month = jul,

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doi = "10.1007/s10600-015-1382-9",

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TY - JOUR

T1 - Natural Pseudoguaianolides Prepared from Damsin

AU - Villagomez, R.

AU - Quiroz, M.

AU - Tito, A.

AU - Sterner, O.

AU - Almanza, G. R.

PY - 2015/7/22

Y1 - 2015/7/22

N2 - Damsin (1) is a pseudoguaianolide sesquiterpene possessing potent biological activities, reported as a metabolite of several medicinal plants belonging to the genus Ambrosia together with related compounds. Starting from 1, which can be isolated in good amounts from Ambrosia arborescens, the five natural pseudoguaianolides ambrosin (2), isodamsin (3), 3α-hydroxydamsin (4), 3α-acetoxydamsin (5), and 11β,13-dihydrodamsin (8) were prepared by regio- and stereo-selective synthetic modifications.

AB - Damsin (1) is a pseudoguaianolide sesquiterpene possessing potent biological activities, reported as a metabolite of several medicinal plants belonging to the genus Ambrosia together with related compounds. Starting from 1, which can be isolated in good amounts from Ambrosia arborescens, the five natural pseudoguaianolides ambrosin (2), isodamsin (3), 3α-hydroxydamsin (4), 3α-acetoxydamsin (5), and 11β,13-dihydrodamsin (8) were prepared by regio- and stereo-selective synthetic modifications.

KW - ambrosanolides

KW - damsin

KW - derivatization

KW - pseudoguaianolides

KW - semi-synthesis

KW - sesquiterpene lactones

UR - http://www.scopus.com/inward/record.url?scp=84938991384&partnerID=8YFLogxK

U2 - 10.1007/s10600-015-1382-9

DO - 10.1007/s10600-015-1382-9

M3 - Artículo

AN - SCOPUS:84938991384

VL - 51

SP - 675

EP - 680

JO - Chemistry of Natural Compounds

JF - Chemistry of Natural Compounds

SN - 0009-3130

IS - 4

ER -

Natural Pseudoguaianolides Prepared from Damsin

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