TY - JOUR
T1 - Natural products as trypanocidal, antileishmanial and antimalarial drugs.
AU - Fournet, Alain
AU - Muñoz Ortiz, Victoria
PY - 2002/11
Y1 - 2002/11
N2 - Parasitic diseases caused by protozoa as Leishmania, Trypanosome or Plasmodium are responsible for more than three millions deaths annually throughout the developing countries. This review covers recent studies on plant-secondary metabolites isolated from medicinal plants and that have demonstrated moderate to high activity in in vitro and in vivo bioassays against these protozoa. The biological activity of the last promising antiparasitic leads are described.
AB - Parasitic diseases caused by protozoa as Leishmania, Trypanosome or Plasmodium are responsible for more than three millions deaths annually throughout the developing countries. This review covers recent studies on plant-secondary metabolites isolated from medicinal plants and that have demonstrated moderate to high activity in in vitro and in vivo bioassays against these protozoa. The biological activity of the last promising antiparasitic leads are described.
UR - http://www.scopus.com/inward/record.url?scp=0036833567&partnerID=8YFLogxK
U2 - 10.2174/1568026023393011
DO - 10.2174/1568026023393011
M3 - Artículo de revisión
C2 - 12171582
AN - SCOPUS:0036833567
VL - 2
SP - 1215
EP - 1237
JO - Current Topics in Medicinal Chemistry
JF - Current Topics in Medicinal Chemistry
SN - 1568-0266
IS - 11
ER -