The Pensamiento Granitoid Complex (PGC), located in the northern part of the eastern Precambrian shield of Bolivia, is tectonically assigned to the Rondonian-San Ignacio Province (1.55-1.30 Ga) of the Amazonian Craton that is made up by Archean and Proterozoic provinces. The Proterozoic ones result from accretionary orogens that become successively younger southwestwards, such as the Rondonian/San Ignacio (1.37-1.32 Ga) and the Sunsás orogenies (1.20-1.00 Ga). The PGC crops out mainly on the "Paragua craton" bounded to the south by the Sunsás belt, and composed of granites and subvolcanic terms, and subordinately of syenites, granodiorites, tonalites, trondhjemites and diorites as orogenic representatives of the Rondonian/San Ignacio Orogeny, intrusive into the Lomas Maneches (ca. 1.68 Ga) and Chiquitania (ca. 1.7 Ga) complexes. Thirteen whole rock chemical analyses for major, trace and REE elements were performed for the La Junta, San Martín, Diamantina, Porvernir, San Cristobal, Piso Firme plutons of the PGC. The negative trends of MgO, Al2O3 and CaO contents with increasing SiO 2 suggest that fractional crystallization played an important role in the petrogenesis of the investigated rocks. The data also indicate a mainly peraluminous, sub-alkaline to high-K calc-alkaline composition, and fractionated LREE/HREE patterns are consistent with a magmatic arc character for these plutons. SHRIMP U-Pb zircon ages of the La Junta and San Martín syn-to late-kinematic plutons are 1347 ± 21 Ma and 1373 ± 20 Ma respectively, and the Sm-Nd TDM model ages are between 1.9 to 2.0 Ga, while εNd(1330) values range from +1.8 to-4.3, respectively. In addition, the late-to post-kinematic Diamantina pluton yields SHRIMP U-Pb zircon age of 1340 ± 20 Ma, and variable Sm-Nd TDM model ages (1.6 to 1.9 Ga) and εNd(1330) values (+0.4 to-1.2) that are comparable with previous results found for other coeval plutons. The Porvenir, San Cristobal and Piso Firme plutons show εNd(1330) signatures varying from +1.5 to +2.7, in agreement with a plutonic arc setting as is suggested for the Diamantina pluton. Integrated interpretation of the geochemical and isotopic data coupled with new geologic correlations of the PGC with contemporary units in the Brazilian counterpart establishes one Mesoproterozoic magmatic arc in the evolution of the Rondonian-San Ignacio province.