Natural products as trypanocidal, antileishmanial and antimalarial drugs.

Alain Fournet, Victoria Muñoz Ortiz

Research output: Contribution to journalReview articlepeer-review

115 Scopus citations

Abstract

Parasitic diseases caused by protozoa as Leishmania, Trypanosome or Plasmodium are responsible for more than three millions deaths annually throughout the developing countries. This review covers recent studies on plant-secondary metabolites isolated from medicinal plants and that have demonstrated moderate to high activity in in vitro and in vivo bioassays against these protozoa. The biological activity of the last promising antiparasitic leads are described.

Original languageEnglish
Pages (from-to)1215-1237
Number of pages23
JournalCurrent Topics in Medicinal Chemistry
Volume2
Issue number11
DOIs
StatePublished - Nov 2002
Externally publishedYes

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