Effect of early, short-term supplementation on weight and linear growth of 4-7-mo-old infants in developing countries: A four-country randomized trial

Kirsten B. Simondon, Agnes Gartner, Jacques Berger, André Cornu, Jean Pierre Massamba, José Luis San Miguel Simbrón, Coudy Ly, Isabelle Missotte, François Simondon, Pierre Traissac, Francis Delpeuch, Bernard Maire

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

The effect of supplementation on growth was tested by means of four similar controlled randomized trials in the Congo (n = 120), Senegal (n = 110), Bolivia (n = 127), and New Caledonia (n = 90). Four-month-old infants were randomly allocated to supplement or control groups. A cereal-based precooked porridge was offered twice daily for 3 mo and consumption was monitored. Both groups were free to eat local food. At 7 mo of age, all infants were still breast-fed in the Congo, Senegal, and Bolivia compared with 47% in New Caledonia. Mean daily consumption of the supplement varied among countries (558-790 kJ/d). Mean length at 4 mo was lowest in Bolivia, higher in Senegal and the Congo, and near the National Center for Health Statistics reference in New Caledonia. The mean 4-7-mo length increment was 0.48 cm higher for supplemented than for control infants in Senegal (P < 0.05), whereas weight increments did not differ. No significant effect was found in the other countries.

Original languageEnglish
Pages (from-to)537-545
Number of pages9
JournalAmerican Journal of Clinical Nutrition
Volume64
Issue number4
DOIs
StatePublished - Oct 1996

Keywords

  • controlled trial
  • developing countries
  • growth disorders
  • infancy
  • intervention
  • Nutritional supplementation
  • recumbent length

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