Cytotoxic and antiprotozoal activity of flavonoids from Lonchocarpus spp.

R. Borges-Argáez; L. Balnbury; A. Flowers; A. Giménez-Turba; G. Ruiz; P. G. Waterman; L. M. Peña-Rodríguez

doi:10.1016/j.phymed.2006.11.027

Cytotoxic and antiprotozoal activity of flavonoids from Lonchocarpus spp.

R. Borges-Argáez, L. Balnbury, A. Flowers, A. Giménez-Turba, G. Ruiz, P. G. Waterman, L. M. Peña-Rodríguez

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

A number of flavonoids isolated from Lonchocarpus spp. were evaluated for their antiprotozoal and cytotoxic activity. Flavone 6 and chalcone 7 were found to be the most active against Leishmania parasites and against cell cultures of Leukemia P388DI and adenocarcinoma prostate PC-3.

Original language	English
Pages (from-to)	530-533
Number of pages	4
Journal	Phytomedicine
Volume	14
Issue number	7-8
DOIs	https://doi.org/10.1016/j.phymed.2006.11.027
State	Published - 6 Aug 2007

Keywords

Antiprotozoal activity
Chalcone
Cytotoxic activity
Flavone
Flavonoids
Lonchocarpus

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10.1016/j.phymed.2006.11.027

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title = "Cytotoxic and antiprotozoal activity of flavonoids from Lonchocarpus spp.",

abstract = "A number of flavonoids isolated from Lonchocarpus spp. were evaluated for their antiprotozoal and cytotoxic activity. Flavone 6 and chalcone 7 were found to be the most active against Leishmania parasites and against cell cultures of Leukemia P388DI and adenocarcinoma prostate PC-3.",

keywords = "Antiprotozoal activity, Chalcone, Cytotoxic activity, Flavone, Flavonoids, Lonchocarpus",

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AU - Borges-Argáez, R.

AU - Balnbury, L.

AU - Flowers, A.

AU - Giménez-Turba, A.

AU - Ruiz, G.

AU - Waterman, P. G.

AU - Peña-Rodríguez, L. M.

PY - 2007/8/6

Y1 - 2007/8/6

N2 - A number of flavonoids isolated from Lonchocarpus spp. were evaluated for their antiprotozoal and cytotoxic activity. Flavone 6 and chalcone 7 were found to be the most active against Leishmania parasites and against cell cultures of Leukemia P388DI and adenocarcinoma prostate PC-3.

AB - A number of flavonoids isolated from Lonchocarpus spp. were evaluated for their antiprotozoal and cytotoxic activity. Flavone 6 and chalcone 7 were found to be the most active against Leishmania parasites and against cell cultures of Leukemia P388DI and adenocarcinoma prostate PC-3.

KW - Antiprotozoal activity

KW - Chalcone

KW - Cytotoxic activity

KW - Flavone

KW - Flavonoids

KW - Lonchocarpus

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DO - 10.1016/j.phymed.2006.11.027

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SN - 0944-7113

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EP - 533

JO - Phytomedicine

JF - Phytomedicine

IS - 7-8

ER -

Cytotoxic and antiprotozoal activity of flavonoids from Lonchocarpus spp.

Abstract

Keywords

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