Cytotoxic and antiprotozoal activity of flavonoids from Lonchocarpus spp.

R. Borges-Argáez, L. Balnbury, A. Flowers, A. Giménez-Turba, G. Ruiz, P. G. Waterman, L. M. Peña-Rodríguez

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

A number of flavonoids isolated from Lonchocarpus spp. were evaluated for their antiprotozoal and cytotoxic activity. Flavone 6 and chalcone 7 were found to be the most active against Leishmania parasites and against cell cultures of Leukemia P388DI and adenocarcinoma prostate PC-3.

Original languageEnglish
Pages (from-to)530-533
Number of pages4
JournalPhytomedicine
Volume14
Issue number7-8
DOIs
StatePublished - 6 Aug 2007

Keywords

  • Antiprotozoal activity
  • Chalcone
  • Cytotoxic activity
  • Flavone
  • Flavonoids
  • Lonchocarpus

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