TY - JOUR
T1 - Antimalarial activity and cytotoxicity of (-)-roemrefidine isolated from the stem bark of Sparattanthelium amazonum
AU - Muñoz Ortiz, Victoria
AU - Sauvain, Michel
AU - Mollinedo Portugal, Patricia Andrea
AU - Callapa, J.
AU - Rojas, I.
AU - Gimenez Turba, Alberto José
AU - Valentin, A.
AU - Mallié, M.
PY - 1999
Y1 - 1999
N2 - (-)-Roemrefidine, an aporphine alkaloid isolated from Sparattanthelium amazonum Martius (Hernandiaceae) a vine from Bolivia, has been found to be active against both resistant and sensitive strains of Plasmodium falciparum in vitro and against P. berghei in mice. The compound demonstrated no cytotoxic activity against three cell lines (KB, HEp-2 and HeLa).
AB - (-)-Roemrefidine, an aporphine alkaloid isolated from Sparattanthelium amazonum Martius (Hernandiaceae) a vine from Bolivia, has been found to be active against both resistant and sensitive strains of Plasmodium falciparum in vitro and against P. berghei in mice. The compound demonstrated no cytotoxic activity against three cell lines (KB, HEp-2 and HeLa).
UR - http://www.scopus.com/inward/record.url?scp=0032994522&partnerID=8YFLogxK
U2 - 10.1055/s-2006-960808
DO - 10.1055/s-2006-960808
M3 - Artículo
C2 - 10418333
AN - SCOPUS:0032994522
VL - 65
SP - 448
EP - 449
JO - Planta Medica
JF - Planta Medica
SN - 0032-0943
IS - 5
ER -