An Efficient, Robust, and Inexpensive Grinding Device for Herbal Samples Like Cinchona Bark

Steen Honoré Hansen, Else Holmfred, Claus Cornett, Carla Maldonado, Nina Rønsted

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

An effective, robust, and inexpensive grinding device for the grinding of herb samples like bark and roots was developed by rebuilding a commercially available coffee grinder. The grinder was constructed to be able to provide various particle sizes, to be easy to clean, and to have a minimum of dead volume. The recovery of the sample when grinding as little as 50 mg of crude Cinchona bark was about 60%. Grinding is performed in seconds with no rise in temperature, and the grinder is easily disassembled to be cleaned. The influence of the particle size of the obtained powders on the recovery of analytes in extracts of Cinchona bark was investigated using HPLC.

Original languageEnglish
Pages (from-to)369-376
Number of pages8
JournalScientia Pharmaceutica
Volume83
Issue number2
DOIs
StatePublished - 2015
Externally publishedYes

Bibliographical note

Publisher Copyright:
© Hansen et al.

Keywords

  • Bark and root
  • Cinchona bark
  • Grinding
  • HPLC

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