Twelve alkaloids have been isolated from bulbs of Brunsvigia orientalis. 1-Epibowdensine, 1-epidemethoxybowdensine and 1-epidecacetylbowdensine are reported here for the first time. The structure and stereochemistry of these new alkaloids have been determined by physical and spectroscopic methods. The 1H and 13C NMR spectra of 6-hydroxycrinamine (both epimers) and crinamidine were completely assigned by means of 2D NMR techniques.
Bibliographical noteFunding Information:
Universitats i Recerca, Generalitat de Catalunya. W.E.C. and S.M. thank the University of Cape Town for financial support. Thanks are also due to M. Viviers for the collection and authentication of plant material. G.R.A. thanks the Instituto de Cooperaci6n Ibero-americana for the provision of a research fellowship.
Acknowledgements--Part of this work was supported financially by CICYT and the Comissionat per a
- 1- epibowdensine
- Brunsvigia orientalis
- buphan idrine