A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Altenos Indians

Victoria Muñoz Ortiz; M. Sauvain; G. Bourdy; S. Arrázola; J. Callapa; Grace Ruiz; J. Choque; E. Deharo

doi:10.1016/S0378-8741(99)00191-9

A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Altenos Indians

Victoria Muñoz Ortiz, M. Sauvain, G. Bourdy, S. Arrázola, J. Callapa, Grace Ruiz, J. Choque, E. Deharo

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

A total of 40 plant extracts traditionally used by the Altenos Indians, a native community living between the Andean block and the tropical valleys of Bolivia, were screened for antimalarial activity in vitro on Plasmodium falciparum chloroquine resistant (Indo) strain, and in vivo on rodent malaria Plasmodium vinckei petteri. Eleven extracts displayed good or moderate activity in vivo, and ten extracts good or very good antimalarial activity in vitro. Results of the screening are discussed here, in relation with the traditional use of plants. Copyright (C) 2000 Elsevier Science Ireland Ltd.

Original language	English
Pages (from-to)	123-131
Number of pages	9
Journal	Journal of Ethnopharmacology
Volume	71
Issue number	1-2
DOIs	https://doi.org/10.1016/S0378-8741(99)00191-9
State	Published - Jul 2000
Externally published	Yes

Bibliographical note

Funding Information:
The project was financed by FONAMA-EIA (Fondo Nacional para el Medio Ambiente, Cuenta Iniciativa para las Americas, Bolivia), IRD (l’institut de Recherche pour le Développement, France), UMSA (Universidad Mayor de San Andrés, La Paz, Bolivia), IBBA (Instituto Boliviano de Biologia de Altura, La Paz, Bolivia), the Ministry of French Foreign Affairs, and IFS (International Foundation for Sciences). The authors wish to thank B. Weniger for kindly help in the bibliographical search, and Rosy Chávez de Michel and the National Herbarium of Bolivia for helping in the management and determination of vouchers. We express our thanks to the members of the Alteños communities who were willing to share with us their knowledge about plants.

Keywords

Altenos
Antimalarial agents
Bolivia
Plasmodium
Quechua
Raqaypampenos
Traditional medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0378-8741(99)00191-9

Cite this

Muñoz Ortiz, V., Sauvain, M., Bourdy, G., Arrázola, S., Callapa, J., Ruiz, G., Choque, J., & Deharo, E. (2000). A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Altenos Indians. Journal of Ethnopharmacology, 71(1-2), 123-131. https://doi.org/10.1016/S0378-8741(99)00191-9

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abstract = "A total of 40 plant extracts traditionally used by the Altenos Indians, a native community living between the Andean block and the tropical valleys of Bolivia, were screened for antimalarial activity in vitro on Plasmodium falciparum chloroquine resistant (Indo) strain, and in vivo on rodent malaria Plasmodium vinckei petteri. Eleven extracts displayed good or moderate activity in vivo, and ten extracts good or very good antimalarial activity in vitro. Results of the screening are discussed here, in relation with the traditional use of plants. Copyright (C) 2000 Elsevier Science Ireland Ltd.",

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note = "Funding Information: The project was financed by FONAMA-EIA (Fondo Nacional para el Medio Ambiente, Cuenta Iniciativa para las Americas, Bolivia), IRD (l{\textquoteright}institut de Recherche pour le D{\'e}veloppement, France), UMSA (Universidad Mayor de San Andr{\'e}s, La Paz, Bolivia), IBBA (Instituto Boliviano de Biologia de Altura, La Paz, Bolivia), the Ministry of French Foreign Affairs, and IFS (International Foundation for Sciences). The authors wish to thank B. Weniger for kindly help in the bibliographical search, and Rosy Ch{\'a}vez de Michel and the National Herbarium of Bolivia for helping in the management and determination of vouchers. We express our thanks to the members of the Alte{\~n}os communities who were willing to share with us their knowledge about plants.",

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Muñoz Ortiz, V, Sauvain, M, Bourdy, G, Arrázola, S, Callapa, J, Ruiz, G, Choque, J & Deharo, E 2000, 'A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Altenos Indians', Journal of Ethnopharmacology, vol. 71, no. 1-2, pp. 123-131. https://doi.org/10.1016/S0378-8741(99)00191-9

A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Altenos Indians. / Muñoz Ortiz, Victoria; Sauvain, M.; Bourdy, G. et al.

In: Journal of Ethnopharmacology, Vol. 71, No. 1-2, 07.2000, p. 123-131.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Altenos Indians

AU - Muñoz Ortiz, Victoria

AU - Sauvain, M.

AU - Bourdy, G.

AU - Arrázola, S.

AU - Callapa, J.

AU - Ruiz, Grace

AU - Choque, J.

AU - Deharo, E.

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PY - 2000/7

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N2 - A total of 40 plant extracts traditionally used by the Altenos Indians, a native community living between the Andean block and the tropical valleys of Bolivia, were screened for antimalarial activity in vitro on Plasmodium falciparum chloroquine resistant (Indo) strain, and in vivo on rodent malaria Plasmodium vinckei petteri. Eleven extracts displayed good or moderate activity in vivo, and ten extracts good or very good antimalarial activity in vitro. Results of the screening are discussed here, in relation with the traditional use of plants. Copyright (C) 2000 Elsevier Science Ireland Ltd.

AB - A total of 40 plant extracts traditionally used by the Altenos Indians, a native community living between the Andean block and the tropical valleys of Bolivia, were screened for antimalarial activity in vitro on Plasmodium falciparum chloroquine resistant (Indo) strain, and in vivo on rodent malaria Plasmodium vinckei petteri. Eleven extracts displayed good or moderate activity in vivo, and ten extracts good or very good antimalarial activity in vitro. Results of the screening are discussed here, in relation with the traditional use of plants. Copyright (C) 2000 Elsevier Science Ireland Ltd.

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KW - Antimalarial agents

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KW - Plasmodium

KW - Quechua

KW - Raqaypampenos

KW - Traditional medicine

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M3 - Artículo

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AN - SCOPUS:0343603536

VL - 71

SP - 123

EP - 131

JO - Journal of Ethnopharmacology

JF - Journal of Ethnopharmacology

SN - 0378-8741

IS - 1-2

ER -

A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part III. Evaluation of the antimalarial activity of plants used by Altenos Indians

Abstract

Bibliographical note

Keywords

UN SDGs

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